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J Urol 163 : 9599 Levine LA et al

Toxicol Appl Pharmacol (2015) 282:617

Incidence, predictability, and pathogenesis of amiodarone-induced thyrotoxicosis and hypothyroidism

More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, and aminolevulinic acid