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Therefore, adjusting the cargo of exosomes and/or engineering their spreading pathways could target cancer cells (especially CSCs) or the TME in order to induce ferroptosis, thus achieving a positive therapeutic outcome

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Thereby, the rapid and then sustained outcome is functionally improved minor vessels, successfully taking the function of disabled major vessels, reestablishing reorganized blood flow and functioning even in the worst circumstances [18,19,20,21,22,23,24,25,26,27,28,29,30]