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Por otro lado, tambin hay un grupo de neuronas con efecto contrario u anorexgeno, que expresan pptidos derivados de la proopiomelanocortina (POMC) y el transcrito regulado por cocana y anfetamina (CART), cuyo producto de secrecin principal es la hormona estimulante de melanocitos alfa (-MSH), el cual se une a su receptor de melanocortina-4 (MC4R) ubicados en el ncleo paraventricular, promoviendo la saciedad 8,9

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