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Key Research Areas

We recommend 1 x 1ml shot once a week for 4 weeks and then once a month.

Combined NNMT inhibitor treatment with reduced-calorie diet achieved 6.3 g cumulative weight loss versus 2.9 g with diet alone, and fat mass reduction was ten-fold greater with treatment (~29.3%) compared to diet switch alone (2.9%), while restoring fatty liver profiles to lean-control levels (Sampson et al., 2021)

While B12 is water-soluble with no established upper safe limit (according to NHS and EFSA guidance), this does not preclude the possibility of adverse reactions, particularly from injectable forms