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Figure 2 3.1 Neutrophils Neutrophil granulocytes are the first line of defense against inflammation in tissues, utilizing phagocytosis, degranulation, and generation of neutrophil extracellular traps (NETs) to combat pathogens

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- protects against oxidative stress - has anti-inflammatory effects - supports liver detoxification Deficient glutathione underlies the oxidative stress in aging Here's how to make enough glutathione PMID: 34439468 Glutathione synthesis is rate-limited by glycine (PMID: 29559876) Taking N-acetylcysteine (NAC) and glycine has been shown to increase glutathione levels (PMID: 17602868

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Studies have shown that ERCs can induce the polarization of M2 macrophages, tolerogenic dendritic cells, and regulatory T and B cells both in vivo and in vitro