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Seek routine GP appointment if you experience: Persistent unexplained fatigue lasting several weeks despite adequate rest Ongoing pins and needles or numbness in hands or feet Difficulty with memory, concentration, or cognitive function Persistent sore tongue or recurrent mouth ulcers Unexplained mood changes or low mood Pale skin or symptoms of anaemia (breathlessness, palpitations) These symptoms warrant investigation but are not typically medical emergencies

Bariatric surgery (e.g., gastric bypass or sleeve gastrectomy) is an option for those with severe obesity

10.1016/j.toxlet.2021.04.018 29 GabayC.SmithM.EidlenD.ArendW

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