MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling
Studies have shown that supplementation with about 20mg daily can improve cognitive function in healthy people after just 12 weeks.44 That same dose can also upregulate mitochondrial biogenesis, improving cellular health.45 B vitamin complex A large-scale systematic review and meta-analysis of B vitamin studies from 2022 found that B vitamins could both benefit cognitive function and slow cognitive decline.46 Another meta-analysis from 2023 that looked specifically at older adults found that supplementation significantly reduced homocysteine levels (a marker of inflammation) but didnt slow declines in cognitive function.47 Ultimately, this shows that B vitamins may play a critical role in your cognitive health, perhaps depending on genetics or whether you suffer from a deficiency
The precise regulatory mechanism by which IGF-1 regulates lifespan and healthy lifespan requires further research
It sounds like glutathione use from free radicals and oxidative stress from exercise, and damage, and a lot of things that can contribute to that, not that that's good, but at least the glutathione can be recycled
Zonulin modulates the tight junctions between cells in the intestinal lining, essentially controlling what passes through the gut wall
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