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Furthermore, it was demonstrated that GLP-1 receptor plays a regulatory role in the hippocampal function and GLP-1 receptor agonists enhanced GABAA signaling through pre-and postsynaptic mechanisms in rats [57], while exendin-4 therapy normalized cognitive dysfunction and improved impaired hippocampal synaptic plasticity in a mice model of diet-induced obesity [58]

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GLP-1 medications linked to hypotension risk GLP-1 medications are associated with an increased incidence of hypotensive events in patients taking two or more hypertension treatments, according to a large retrospective observational study

EDRF is essential for regulating circulation and ensuring blood flow to vital organs such as the heart, kidneys, and brain

Potential Future Treatments and Biomarker Development What is the role of leucovorin and folate deficiency in autism