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3.3.2 Effect of metformin on offspring malformations in patients with polycystic ovary syndrome The period of early pregnancy is critical for organogenesis and the potential teratogenic effects of drugs

Lee et al., 1997)

After six months, high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were significantly increased in the low-risk group, while the low-density lipoprotein cholesterol (LDL-C)/HDL-C ratio decreased in the high-risk group, suggesting favorable lipid modulation

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