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This article systematically explores the core mechanisms of ferroptosis, including iron overload catalyzing lipid peroxidation via the Fenton reaction, dysregulation of antioxidant systems (such as GPX4 and FSP1), and their associations with gastric cancer cell proliferation, metastasis, and resistance

[1] Berberine is a bioactive alkaloid compound extracted from several plants, including Berberis species (barberry), goldenseal, and Chinese goldthread

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Hence, a possible explanation for the increased sperm concentration and viability in our study might be attributed to an increased lactate production by the Sertoli cells or increased GLUT protein levels and activities, although further studies are required to validate this