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Amgen has emphasized that lower doses and adjusted dose escalation schedules have improved tolerability, especially related to gastrointestinal side effects like nausea and constipation, which are common issues with all GLP-1 therapies

Q: Is evening cagrilintide dosing safe for people with GERD or acid reflux

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Gastrointestinal side effects represent the most common adverse events across the GLP-1 class