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Therapeutic concentrations of exenatide are achieved after 2 weeks, while steady-state concentrations of exenatide in the plasma are reached after 6 to 10 weeks [17,67]

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CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) and growth hormone secretagogue (GHS) that was developed in the early 2000s by Canadian biotech firm ConjuChem Technologies [1]

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The standard cagrilintide monotherapy titration follows this schedule: 0.25 mg weekly for weeks 1-4, then 0.5 mg for weeks 5-8, then 1.0 mg for weeks 9-12, then 1.7 mg for weeks 13-16, and finally 2.4 mg for week 17 onward as the maintenance dose