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Remarkably, the two top enriched GO terms within the top 100 differentially regulated genes in hematopoietic stem cells from Aldh2 / Adh5 / mice correspond to cellular response to oxygen-containing compounds (GO1901700 and GO1901701) 10 , suggesting oxidative stress might play an important role in the onset of IBMFS/AMeD phenotypes

Mitochondrial dysfunction Sperm motility depends on the process of oxidative phosphorylation, which is how mitochondria produce ATP

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