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Although it cannot yet be determined whether vitamin B 12 deficiency plays a causal role in depression, it may be beneficial to screen for vitamin B 12 deficiency in older individuals as part of a medical evaluation for depression

Cagrilintides promise is as a stack partner to deepen satiety without relying on incretin pathways alone

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However, the B12 itself can stay in your system longer, with effects on red blood cell production and nerve health lasting for weeks or months, depending on your deficiency and injection frequency

However, no human studies have examined truly long-term use extending over years or decades