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At the level of expression regulation, Pickarts transcriptomic studies indicate that the compound affects the expression of hundreds of genes related to tissue repair, antioxidant defense and anti-inflammation in profile analyses, it acted as a modulator shifting the expression pattern towards the repair profile (Pickart et al
doi: 10.1002/osp4.342 39 GaoLHuangHZhangLZhangNFuYZhuDet al
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TB-500's parent Thymosin -4 has been administered at micrograms-per-kilogram parenteral dosing in cardiac and corneal model systems
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