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Compounds such as alpha-chloroacetamide-based inhibitors achieve this by covalently binding to a cysteine residue in the SAM-binding pocket of NNMT 202

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When administered by trained medical professionals, glutathione is generally safe with minimal side effects, usually limited to temporary irritation at the injection site

CSF provides a particularly informative substrate for investigating neurological disease because it directly reflects processes occurring within the central nervous system