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Both groups improved significantly by ~20% compared with baseline at d 28 (mean decreases of ARA 290 = 3.9 1.9 and placebo = 3.7 1.5

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A randomised non-comparative phase II trial of cixutumumab (IMC-A12) or ramucirumab (IMC-1121B) plus mitoxantrone and prednisone in men with metastatic docetaxel-pretreated castration-resistant prostate cancer

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1 In an animal model study combined with cultured tendon fibroblast experiments, research examined BPC-157's effects on tendon tissue outgrowth, focal adhesion kinase (FAK) and paxillin signaling, fibroblast migration markers, and cell survival under oxidative stress conditions