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They compared weight loss outcomes in people taking chitosan supplements with those of people taking a placebo Results showed that chitosan supplementation slightly reduced body weight and body mass index (BMI) when paired with a calorie-restricted diet and physical activity These results support the findings of a similar, older review, which found that chitosan supplements may be more effective than a placebo as part of a short-term treatment plan for overweight and obesity Both reviews noted improvements in cholesterol levels and blood pressure Reduced cholesterol levels Chitosan may have a greater impact on cholesterol levels than on weight loss