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Aging Cell (2020) 19(11):e13261

These findings establish a critical role for GSH in promoting Rickettsia cell division and pathogenesis, contributing to the concept that GSH plays multifaceted roles in the fitness of intracellular pathogens

Charles Brenner, who discovered nicotinamide riboside as an NAD+ precursor, conducted a 2016 clinical trial showing oral NR supplementation safely increased human blood NAD+ levels up to 2.7-fold [14]