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doi:10.1093/ajcn/nqaa259 Liu F, Edelmann M, Piironen V, Kariluoto S

Wnt signalling plays an important role in the self-renewal of some tissues in mammals

These widespread effects include upregulation of genes involved in matrix synthesis, cell adhesion, growth factor signaling, and tissue remodeling, alongside downregulation of genes associated with inflammation, oxidative stress, and cellular senescence

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The pilot study reveled that RJ pretreatment at the doses of 34, 85 and 170 mg/kg markedly prevented pathological alternations in the kidney of CdCl 2 intoxicated mice (data have not shown)