Use of risk prediction equations in earlier stages of disease The working group also considered the need for early identification and intervention in people with high-risk CKD and preserved eGFR (CKD stages G1 to G3) and suggests the use of alternative equations that predict the risk of a 40% decline in eGFR or for kidney failure in this population

The most common side effects of Zepbound in clinical trials when compared to placebo include: Nausea Diarrhea Vomiting Indigestion Constipation Some other possible side effects of Zepbound include: Burping Fatigue Stomach pain Hair loss Injection site reactions Dizziness Zepbound may also cause more serious side effects including: Serious allergic reactions, including: hives, swelling of your throat and tongue, trouble breathing Increased risk of thyroid cancer or thyroid tumors Pancreatitis (inflammation of your pancreas) Kidney damage including kidney failure Gallbladder problems including gallstones Hypoglycemia (dangerously low blood sugar) Vision changes in people with type 2 diabetes (diabetic retinopathy) Worsening depression or suicidal thoughts Disclaimer: These are not all of the possible adverse events of Zepbound

You'll need to see a doctor frequently when taking semaglutide as a weight reduction treatment due to the possibility of side effects or interactions with other prescription medications and herbal supplements
Zepbound, semaglutide GLP-1, and Wegovy have all been FDA-approved through studies to help non-diabetic patients with medical weight loss, as long as a patient has a BMI of 30 or greater, with considerations for patients with a BMI of 27 or higher that have other health conditions that could impede weight loss such as hypertension, high cholesterol and hormonal conditions like PCOS
5.5 Appetite Control in Binge Eating Disorders By modulating satiety pathways, it may reduce compulsive eating behaviors