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Importantly, increasing the endogenous production of GLP-1 by different mechanisms or by increasing the number of intestinal L-cells that tend to produce this hormone may be another effective therapeutic approach to managing T2DM

Thus, modulating the bioavailability and resorption of bile acids, the microbiota impacts on enterohepatic bile acid-signaling and greatly impacts the whole-body metabolic homeostasis (199)

3.3.2.1 Urolithin A Urolithin A, a natural gut metabolite of ellagic acid and ellagitannins, rich in nuts, is a safe mitophagy activator (Andreux et al., 2019

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sIPSC parameters (frequency, median amplitude, 1090% median rise time, 63% median decay time and median charge transfer) were automatically analyzed by the MiniAnalysis software