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First, epidemiological data reveal that patients with T2D and cardiovascular disease receiving GLP-1RAs have substantial reductions in the risk of developing all-cause dementia

GLP-1R belongs to the class B family of G-protein-coupled receptors (GPCRs), which utilize a distinct peptide-binding mechanism compared to small-molecule GPCRs

It is worth noting the differences in approach to secondary indications by the FDA vs

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