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Patients eligible to enter the trial were: 50 years of age or older and with established CV disease or CKD

10.1007/s10815-020-01906-3 18 Garrido-MaraverJ.CorderoM

For example, a tri-functional copper-based MOF nanozyme developed by Dong et al.not only generates ROS but also modulates the redox environment, overcoming chemotherapy resistance in CRC and providing a new therapeutic strategy for future clinical applications [101]