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The tradeoff is larger injection volumes at higher doses

GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed weight management

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No single-receptor or even dual-receptor agonist can replicate this combination, which is why retatrutide produced weight loss numbers that surpassed both Ozempic and tirzepatide in clinical comparisons

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