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Repeated missed doses may result in serious health complications, including impaired kidney function, vision problems, and reduced blood flow to extremities

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It has been shown that patients with the obesity HFpEF phenotype are younger and have lower natriuretic peptide levels 3,6,7 but present with higher NYHA class 4,7 , greater symptom severity, poorer exercise capacity 7,8 and greater systemic inflammation than patients without obesity 7