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B., Nuhoho, S., Ali, S

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A muscle-preserving weight-loss strategy may include: Medical history review Weight and body-composition goals Nutrition planning Protein guidance Resistance-training recommendations Metabolic lab review Hormone and thyroid considerations when appropriate Medication review GLP-1 education Peptide therapy discussion when medically appropriate Ongoing monitoring and adjustment This type of care is especially important for patients who have: Insulin resistance Prediabetes Type 2 diabetes Menopause-related body-composition changes Low energy Low muscle mass A history of repeated dieting Thyroid concerns High stress Poor sleep Prior weight regain Concerns about rapid weight loss For these patients, a generic weight-loss plan is rarely enough

For injectable GLP-1 medications, it does not matter if you have eaten recently or not, as the medication is absorbed into the fat under the skin rather than through the digestive tract

Despite these changes, the bioenergetic features (OCR and ECAR) remained unaffected ( Figure 3i, j )