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15LO1 increases intracellular oxidative potential by lowering GSH and increasing extracellular GSSG To confirm that 15LO1-PEBP1 complex activity alters IL-13induced intracellular GSH levels, we modeled these relationships in vitro by stimulating cultured HAECs (at ALI) with IL-13 for 710 days in the presence and absence of 15LO1 protein (dicer siRNA knockdown [KD] of ALOX15 gene) or enzymatic activity (specific 15LO1 inhibitor BLX2477) (14, 15)

Supplement Facts Serving Size: 1 Capsule Servings Per Container: 30 Daily Value not established

Selenium Selenium is a cofactor of glutathione peroxidase, an antioxidant enzyme active inside of cells that protects our cells from damage by free radicals produced during metabolism

Stories of salicylic acid: a plant defense hormone

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