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Wilkes JM, Clark LE, Herrera JL

Directions: As a dietary supplement, take 1 to 2 capsules daily, preferably with a meal

Similarly, in cells under oxidative stress conditions, activated NRF2 can enhance the expression of MFN1 and MFN2 while degrading DRP2 through the proteasomal pathway, leading to mitochondrial hyperfusion, which temporarily protects cells and alleviates oxidative stress as well as inhibits ferroptosis [109]

Cozza G, Rossetto M, Bosello-Travain V, Maiorino M, Roveri A, Toppo S et al (2017) Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: the polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center