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Baseline measurements found that TNF-alpha and IL-1-beta levels in the APP/PS1 group of mice were much higher than the wild type group of mice

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Secondary antibodies used were goat-anti-mouse-horseradish peroxidase (ThermoFisher Scientific, #31430, used 1:3000) and goat-anti-rabbit horseradish peroxidase (ThermoFisher Scientific, #31460, used 1:3000)

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-MSH and its KPV fragment inhibit TNF--driven NF-B activity in human keratinocytes and dermal fibroblasts, the two main cell types in skin, without triggering pigmentation

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