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One survey shows about 12% of U.S

Patients typically notice appetite reduction within the first few days, with measurable changes appearing within the first month

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Rare: Elevated pancreatic enzyme levels (amylase/lipase) without clinical pancreatitis

Arenas were cleaned with 20% ethanol after each trial to minimize olfactory clues, and mice were placed in a new cage after being tested to prevent modifying the behaviour of untested mice