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Obstructive sleep apnoea is independently associated with the metabolic syndrome but not insulin resistance state

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Research over the past two decades has shown that microbiome composition can influence: Energy extraction from food Fat storage signaling Immune activity Hormone production related to appetite Some microbial populations are associated with increased energy harvest from dietary carbohydrates, which may contribute to weight gain in certain individuals

Boosting it could extend healthy lifespan."[13][3] He advocates for precursors but sees value in inhibitors like 5-Amino-1MQ to maximize NAD+ utility