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Both active and passive vaccinations have been proposed for Alzheimer's disease and other conditions

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Dose-related effects on the rat fetus (structural abnormalities and reduced body weight) occurred only at higher dosages, equal to or greater than 150 mg/kg (more than 2344-times the 10 mg clinical dose, based on AUC), which were associated with maternal toxicity

This is the first step toward developing that knowledge, which will require large-scale, carefully controlled clinical trials." Rasgon is a member of the Stanford Neurosciences Institute