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Several studies have been carried out with longer follow-up periods up to 6 years finding a persistent bone loss (253256)

L., Bolte H

10.1371/journal.pone.0000276 PLoS One 92 HuberR.TononiG.CirelliC

Long-term studies

"With these exploratory findings of SURPASS-4, we are seeing the results of combined GIP/GLP-1 receptor agonists on the kidney function of patients with type 2 diabetes for the very first time," Heerspink said in a statement