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This suggests that a temporary BBB open drug delivery strategy can be effectively and safely performed using this method[178]

The mean age of symptom onset was 36.117.7 years (range, 8~64 years), with 10 cases (55.5%) within the ages 20~49 years

Ethics declarations Ethics approval and consent to participate Approval for this study was obtained from the ethics committee of the French Society of Intensive Care (protocol number, FICS20020231)