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Moderate, steady fat loss with consistent protein intake consistently produces better body composition outcomes than rapid loss with inadequate protein even if the scale moves faster in the short term

Pharmacological: Natural GLP-1: Secreted 5-30 minutes after meals, returns to baseline within 2 hours Weekly injection: Sustained elevation for 168 hours with gradual decline Microdosing: Intermediate pattern with regular, smaller peaks The Case Against: Significant Drawbacks 1

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This observation touches on an important shift occurring alongside the development of these drugs: a changing understanding of obesity

In: Scriver CR, Beaudet AL, Sly WS, Valle D (eds) The Metabolic and Molecular Bases of Inherited Disease