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Currently, GLP-1 receptor agonists are approved for use by people who have type 2 diabetes and/or obesity

One theoretical concern with TB-500 and BPC-157 relates to angiogenesis promotion

Both GIP from intestine K- and GLP-1- from intestine L-cells are mainly stimulated by the ingestion and absorption of carbohydrates and triglycerides or their digestion products

The dispersion between Novo and Lilly again goes to show the incredible power of competition to dictate stock outcomes: despite Novos excellent financial performance since 2023 (31% growth in 2023, 25% growth in 2024, 48% EBIT margins), the stock has declined because of competition: investors think Eli Lilly is the emerging winner within GLP-1s, given the stronger weight loss profile of tirzepatide (Mounjaro/Zepbound) versus semaglutide (Ozempic/Wegovy), and Lillys more attractive weight loss pipeline assets

Real Ozempic users also suggest trying alternatives like Wegovy or compounded semaglutide