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More recently, the anticancer activity of new EA derivates has been tested in antiproliferative assays on two different tumoral cell lines 91

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We highlight how excessive mtROS contribute to oxidative damage, mitochondrial dysfunction, impaired energy metabolism, and activation of key atrophy-related signaling pathways, including FOXO, NF-B, MAPK, the ubiquitin-proteasome system, and the autophagy-lysosome pathway

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