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Infants : Poor muscle tone Poor sucking reflex Poor responsiveness or activeness Distinct facial features Underdeveloped genitals Childhood to adulthood: Food cravings and weight gain Underdeveloped sexual organs Poor growth and physical development Cognitive impairment Speech problems Delayed motor development Behavioral problems Sleep disorders Physical abnormalities What is the cause of the syndrome

Retatrutide is in Phase 3 trials and is not FDA-approved as of June 2026

Arthritis Res Ther, 2011

1988;238(2):343 to 346