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Furthermore, when we counted the number of live cells in si-P65 and si-EAAT3 cells exposed to RSL3 treatment, both cell lines exhibited a dose-dependent increase in cell death in EAAT3-silenced cells (Fig

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In the nucleus, FOXO4 activates the transcription of genes encoding antioxidant enzymes like manganese superoxide dismutase (MnSOD), catalase (CAT), and glutathione peroxidase (GPX)

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