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Available from: Kadowaki T, Isendahl J, Khalid U, Lee SY, Nishida T, Ogawa W, et al

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These selectivity pharmacology studies have established Ipamorelins pentapeptide structure as the reference pharmacophore solution for achieving GHS-R1a-selective GH release and provided the comparative dataset against which all subsequent selective GH secretagogue compounds are evaluated

41,42 The RESPONDER-HF studying this particular subgroup is ongoing (NCT05425459)