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While tirzepatide established superiority over semaglutide in the SURMOUNT-5 trialachieving 20.2% weight loss vs 13.7%indirect network meta-analyses suggest that retatrutide will likely surpass tirzepatide in both absolute and percentage weight reduction

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thus, diabetic patients are more prone to infections, which could increase their need for antibiotics

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Side effects and cautions B12 has no established upper limit due to low toxicity, but injections can have side effects: Common: soreness, redness or swelling at the injection site