Preclinical data suggests that chronic pain may cause significant changes in hippocampal plasticity, including a reduction of new neurons in the hippocampus (a portion of the brain related to learning, memory, mood regulation, and stress response.) It has previously been believed that a person is born with a finite number of neurons which will deteriorate over time
Advanced / Loading Phase (Optional) Some protocols use a higher TB-500 loading dose during the first 24 weeks based on clinical monograph recommendations [5]
Christensen M, Knop FK, Holst JJ, Vilsboll T
[PubMed] [PMC] Fallah F, Mahdavi R (2023) Ameliorating effects of L-carnitine and synbiotic co-supplementation on anthropometric measures and cardiometabolic traits in women with obesity: A randomized controlled clinical trial
Gvozdjakova et al., 2014)