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Intern Info Thibault Roudaire Functional Analysis of a Putative UDP-Glycosyltransferase Involved in the Biosynthesis of Cardiac Glucosides in Erysimum cheiranthoides Project summary: Cardiac glycosides are a class of defense-related plant metabolites that inhibit animal Na+, K+-ATPase membrane ion transporters, and thereby deter certain insect species from feeding or ovipositing on the plants that produce them

DAQs can conjugate with B-crystallin and heat shock protein 27 (HSP27), two small heat-shock chaperone proteins, to promote the cross-linking of B-crystallin and HSP27 and inhibit their chaperone functions [59]

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Common gastrointestinal side effects occur in the majority of patients and include nausea (reported in 20-50% depending on the agent and dose), vomiting, diarrhea, constipation, and abdominal pain

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