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A 2021 randomized, double-blind trial published in Frontiers in Medicine investigated the effects of GLM intervention on biomarkers of cartilage metabolism in patients with joint symptoms

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FAHF-2 (3.3 g) was well tolerated, safe, and inhibited basophil CD63 expression in response to ex vivo stimulation at 6 months, warranting a controlled phase 2 study [28]

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