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TETA is a chelator that specifically binds to Cu2+ ions and has been widely used for the treatment of Wilson's disease (125)

Furthermore, we elucidate a possible mechanism through which naltrexone may attenuate the antidepressant effects of ketamine by demonstrating opioid modulation of ketamine-induced glutamatergic activity

These failures may be traced to the use of inappropriate biomarkers as guides to treatment development