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The 3D printed functional layer (FL) contains catechol, gallium, and biologically active platelet-rich fibrin (PRF) that promotes both tissue and backing layer adhesion to enhance antibacterial effects, angiogenesis, cell growth, and migration thus can be therapeutically used to treat burned wounds [184]

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Medicubes PDRN Caffeine Collagen Eye Patch pairs salmon-derived PDRN with retinol and collagen to help improve the appearance of firmness and smooth the look of fine lines, while caffeine reduces swelling through vasoconstriction, says Hee Jin Kim, MD, a board-certified medical doctor based in Fort Lee, New Jersey

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Consequently, formulators must control exposure to oxygen, light, and reactive ingredients