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Phentermine may also increase resting energy expenditure slightly, though appetite suppression remains the dominant mechanism driving weight loss

In 3T3-L1 cells, expression of TGH is upregulated tenfold upon differentiation of preadipocytes into adipocytes (25) due, at least in part, to transcriptional regulation by the adipogenic transcription factor C/EBP (136)

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Activation of this pathway is associated with hair growth initiation

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