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In the United States, the increased legalization of recreational and medical cannabis by the States has expanded the number of users who consume cannabis regularly and at higher doses [2], which is driven both by the availability of higher potency cannabis products [3] and access to diverse formulations (e.g., edibles, beverages, vaping, and dabbing) [4]

55 The risk of hepatotoxicity is especially increased in individuals administered high doses of 300 mg daily of benzbromarone

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