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In terms of biochemical characteristics, cells undergoing ferroptosis show an imbalance of oxidationreduction levels: a significant increase in intracellular reactive oxygen species (ROS) and a significant decrease in NADPH, and therefore lipid antioxidants can inhibit ferroptosis

The Science Behind High-Dose Vitamin C Research demonstrates that high-dose vitamin C functions differently than the lower concentrations you get from diet or supplements

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doi:10.1021/jf970670x